Vpu binds directly to tetherin and displaces it from nascent virions.
Tetherin (Bst2/CD317/HM1.24) is an interferon-induced antiviral host protein that inhibits the release of many enveloped viruses by tethering virions to the cell surface. The HIV-1 accessory protein, Vpu, antagonizes Tetherin through a variety of proposed mechanisms, including surface downregulation...
Gorde:
| Egile Nagusiak: | , , |
|---|---|
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Public Library of Science (PLoS)
2013-01-01
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| Saila: | PLoS Pathogens |
| Sarrera elektronikoa: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003299&type=printable |
| Etiketak: |
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