SIV Nef proteins recruit the AP-2 complex to antagonize Tetherin and facilitate virion release.
Lentiviral Nef proteins have multiple functions and are important for viral pathogenesis. Recently, Nef proteins from many simian immunodefiency viruses were shown to antagonize a cellular antiviral protein, named Tetherin, that blocks release of viral particles from the cell surface. However, the m...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2011-05-01
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| Series: | PLoS Pathogens |
| Acceso en liña: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002039&type=printable |
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