From neurodevelopment to neurodegeneration: utilizing human stem cell models to gain insight into Down syndrome

Down syndrome (DS), caused by triplication of chromosome 21, is the most frequent aneuploidy observed in the human population and represents the most common genetic form of intellectual disability and early-onset Alzheimer’s disease (AD). Individuals with DS exhibit a wide spectrum of clinical prese...

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Autori principali:	L. Ashley Watson, Hiruy S. Meharena
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2023-05-01
Serie:	Frontiers in Genetics
Soggetti:	down syndrome neurodevelomental disorders neurodegenenerative diseases human tissue cell culture models human stem cells
Accesso online:	https://www.frontiersin.org/articles/10.3389/fgene.2023.1198129/full
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