Sonic Hedgehog Pathway Modulation Normalizes Expression of Olig2 in Rostrally Patterned NPCs With Trisomy 21

The intellectual disability found in people with Down syndrome is associated with numerous changes in early brain development, including the proliferation and differentiation of neural progenitor cells (NPCs) and the formation and maintenance of myelin in the brain. To study how early neural precurs...

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מידע ביבליוגרפי

Principais autores:	Jenny A. Klein, Zhen Li, Sanjeev Rampam, Jack Cardini, Amara Ayoub, Patricia Shaw, Angela L. Rachubinski, Joaquin M. Espinosa, Ella Zeldich, Tarik F. Haydar
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2022-01-01
סדרה:	Frontiers in Cellular Neuroscience
נושאים:	Down syndrome oligodendrocytes Sonic hedgehog isogenic iPSCs brain spinal cord
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fncel.2021.794675/full
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!