Potential role of RhoA GTPase regulation in type interferon signaling in systemic lupus erythematosus

Abstract Objective Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by abnormal activation of the type I interferon (IFN) pathway, which results in tissue inflammation and organ damage. We explored the role of the RhoA GTPase in the type I IFN activation pathway to provide...

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ग्रंथसूची विवरण

मुख्य लेखकों:	Wei Fan, Bo Wei, Xuyan Chen, Yi Zhang, Pingping Xiao, Kaiyan Li, Yi qin Zhang, Jinmei Huang, Lin Leng, Richard Bucala
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	BMC 2024-01-01
श्रृंखला:	Arthritis Research & Therapy
विषय:	Autoimmunity Systemic lupus erythematosus RhoA Type I IFN RhoA/ROCK inhibitor
ऑनलाइन पहुंच:	https://doi.org/10.1186/s13075-024-03263-3
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