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RhoA- and Actin-Dependent Functions of Macrophages from the Rodent Cardiac Transplantation Model Perspective -Timing Is the Essence

The small GTPase RhoA, and its down-stream effector ROCK kinase, and the interacting Rac1 and mTORC2 pathways, are the principal regulators of the actin cytoskeleton and actin-related functions in all eukaryotic cells, including the immune cells. As such, they also regulate the phenotypes and functi...

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Principais autores: Malgorzata Kloc, Ahmed Uosef, Martha Villagran, Robert Zdanowski, Jacek Z. Kubiak, Jarek Wosik, Rafik M. Ghobrial
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-01-01
Serier:Biology
Fag:
RhoA
ROCK
Rac1
actin
macrophage
transplantation
Online adgang:https://www.mdpi.com/2079-7737/10/2/70
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