Potential role of RhoA GTPase regulation in type interferon signaling in systemic lupus erythematosus

Abstract Objective Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by abnormal activation of the type I interferon (IFN) pathway, which results in tissue inflammation and organ damage. We explored the role of the RhoA GTPase in the type I IFN activation pathway to provide...

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主要な著者:	Wei Fan, Bo Wei, Xuyan Chen, Yi Zhang, Pingping Xiao, Kaiyan Li, Yi qin Zhang, Jinmei Huang, Lin Leng, Richard Bucala
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2024-01-01
シリーズ:	Arthritis Research & Therapy
主題:	Autoimmunity Systemic lupus erythematosus RhoA Type I IFN RhoA/ROCK inhibitor
オンライン･アクセス:	https://doi.org/10.1186/s13075-024-03263-3
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