Nanopore sequencing of clonal IGH rearrangements in cell-free DNA as a biomarker for acute lymphoblastic leukemia

BackgroundAcute Lymphoblastic Leukemia (ALL) is the most common pediatric cancer, and patients with relapsed ALL have a poor prognosis. Detection of ALL blasts remaining at the end of treatment, or minimal residual disease (MRD), and spread of ALL into the central nervous system (CNS) have prognosti...

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Detaylı Bibliyografya
Asıl Yazarlar:	Shilpa Sampathi, Yelena Chernyavskaya, Meghan G. Haney, L. Henry Moore, Isabel A. Snyder, Anna H. Cox, Brittany L. Fuller, Tamara J. Taylor, Donglin Yan, Tom C. Badgett, Jessica S. Blackburn
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Frontiers Media S.A. 2022-12-01
Seri Bilgileri:	Frontiers in Oncology
Konular:	B-cell acute lymphoblastic leukemia (B-ALL) central nervous system (CNS) disease clonality minimal residual disease (MRD) relapse VDJ rearrangement
Online Erişim:	https://www.frontiersin.org/articles/10.3389/fonc.2022.958673/full
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!

Nanopore sequencing of clonal IGH rearrangements in cell-free DNA as a biomarker for acute lymphoblastic leukemia

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