A N-terminal Truncated Intracellular Isoform of Matrix Metalloproteinase-2 Impairs Contractility of Mouse Myocardium
The full-length isoform of matrixmetalloproteinase-2 (FL-MMP-2) plays a role in turnover of the cardiac extracellular matrix. FL-MMP-2 is also present intracellularly in association with sarcomeres and, in the setting of oxidative stress, cleaves myofilament proteins with resultant impaired contract...
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| Автори: | , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Frontiers Media S.A.
2014-09-01
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| Серія: | Frontiers in Physiology |
| Предмети: | |
| Онлайн доступ: | http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00363/full |
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