Ablation of matrix metalloproteinase-9 prevents cardiomyocytes contractile dysfunction in diabetics

Elevated expression and activity of matrix metalloproteinase-9 (MMP9) and decreased contractility of cardiomyocytes are documented in diabetic hearts. However, it is unclear whether MMP is involved in the regulation of contractility of cardiomyocytes in diabetic hearts. In the present study, we test...

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Главные авторы:	Priyanka ePrathipati, Naira eMetreveli, Shyam Sundar Nandi, Suresh Chand Tyagi, Paras Kumar eMishra
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2016-03-01
Серии:	Frontiers in Physiology
Предметы:	Diabetes Mellitus Heart Failure Calcium transient Akita Serca-2a
Online-ссылка:	http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00093/full
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