Cardiomyocyte‐enriched OTUD5 alleviates septic cardiomyopathy by promoting NLRP3 deubiquitination and inhibiting NLRP3 inflammasome activation

Abstract Background Septic cardiomyopathy (SCM) is the leading cause of mortality among patients diagnosed with sepsis. Nevertheless, the precise mechanisms underlying its pathogenesis remain poorly understood. Deubiquitinating enzymes (DUBs) play a vital role in various cardiovascular diseases. Met...

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מידע ביבליוגרפי

Principais autores:	Yucheng Jiang, Zhihan Jia, Zhaozheng Zheng, Yingjie Liao, Qingqing Zhao, Wante Lin, Diyun Xu, Naijin Zhang, Guang Liang, Bozhi Ye
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Wiley 2026-07-01
סדרה:	Clinical and Translational Medicine
נושאים:	deubiquitinating enzyme NLRP3 OTUD5 pyroptosis septic cardiomyopathy
גישה מקוונת:	https://doi.org/10.1002/ctm2.70743
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