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USP18 mediates high glucose‐induced cardiomyocyte injury by regulating the JAK/STAT signaling pathway through stabilizing FOXC2 expression

ABSTRACT Background Cardiomyopathy is one of the complications of diabetes, among which myocardial fibrosis is the most typical feature. Ubiquitin‐specific peptidase 18 (USP18) is a deubiquitinating enzyme. Multiple studies suggest that it may have the potential to protect against myocardial injury...

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Bibliografiske detaljer
Principais autores: Zhengrong Xu, Weidong Ren, Jun Gu, Wenjuan Deng, Lijuan Zuo
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2026-05-01
Serier:Journal of Diabetes Investigation
Fag:
Online adgang:https://doi.org/10.1111/jdi.70210
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