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Continuous transport of a small fraction of plasma membrane cholesterol to endoplasmic reticulum regulates total cellular cholesterol

Cells employ regulated transport mechanisms to ensure that their plasma membranes (PMs) are optimally supplied with cholesterol derived from uptake of low-density lipoproteins (LDL) and synthesis. To date, all inhibitors of cholesterol transport block steps in lysosomes, limiting our understanding o...

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Detaylı Bibliyografya
Asıl Yazarlar: Rodney Elwood Infante, Arun Radhakrishnan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications Ltd 2017-04-01
Seri Bilgileri:eLife
Konular:
Online Erişim:https://elifesciences.org/articles/25466
Etiketler: Etiketle
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