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The role of hRev7, the accessory subunit of hPolζ, in translesion synthesis past DNA damage induced by benzo[a]pyrene diol epoxide (BPDE)

<p>Abstract</p> <p>Background</p> <p>DNA polymerase zeta (Polζ) is a specialized DNA polymerase that, unlike classical replicative polymerases, is capable of replicating past DNA lesions, i.e. of performing translesion synthesis (TLS). The catalytic subunit of hPolζ, hRev3, has been shown to play a...

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Bibliografische Detailangaben
Hauptverfasser: Maher Veronica M, McCormick J Justin, Fletcher Kathryn L, Neal Jessica A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2010-12-01
Schriftenreihe:BMC Cell Biology
Online-Zugang:http://www.biomedcentral.com/1471-2121/11/97
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