Effect of endothelium on the anticoagulant activity of a covalent antithrombin-heparin complex
Abstract We developed a covalent antithrombin-heparin complex (ATH) with superior In vivo anticoagulant efficacy compared to non-covalent antithrombin (AT) + unfractionated heparin (H). Previous in vitro studies of ATH, investigating the mechanisms behind its efficacy, were done in the absence of en...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Portfolio
2024-09-01
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| Colección: | Scientific Reports |
| Acceso en línea: | https://doi.org/10.1038/s41598-024-72458-0 |
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