Effect of endothelium on the anticoagulant activity of a covalent antithrombin-heparin complex
Abstract We developed a covalent antithrombin-heparin complex (ATH) with superior In vivo anticoagulant efficacy compared to non-covalent antithrombin (AT) + unfractionated heparin (H). Previous in vitro studies of ATH, investigating the mechanisms behind its efficacy, were done in the absence of en...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Portfolio
2024-09-01
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| Edice: | Scientific Reports |
| On-line přístup: | https://doi.org/10.1038/s41598-024-72458-0 |
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