Rac1 and Cdc42 are regulators of HRas^V12-transformation and angiogenic factors in human fibroblasts

<p>Abstract</p> <p>Background</p> <p>The activities of Rac1 and Cdc42 are essential for HRas-induced transformation of rodent fibroblasts. What is more, expression of constitutively activated mutants of Rac1 and/or Cdc42 is sufficient for their malignant transformation. The role for these two Rho GT...

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Detalhes bibliográficos

Principais autores:	Dao Kim-Hien T, Appledorn Daniel M, O'Reilly Sandra, Maher Veronica M, McCormick J Justin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2010-01-01
Colecção:	BMC Cancer
Acesso em linha:	http://www.biomedcentral.com/1471-2407/10/13
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