Rac1 and Cdc42 are regulators of HRas<sup>V12</sup>-transformation and angiogenic factors in human fibroblasts
<p>Abstract</p> <p>Background</p> <p>The activities of Rac1 and Cdc42 are essential for HRas-induced transformation of rodent fibroblasts. What is more, expression of constitutively activated mutants of Rac1 and/or Cdc42 is sufficient for their malignant transformation. The role for these two Rho GT...
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| Автори: | , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2010-01-01
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| Серія: | BMC Cancer |
| Онлайн доступ: | http://www.biomedcentral.com/1471-2407/10/13 |
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