Partial reversion of the transformed phenotype in HRAS-transfected tumorigenic cells by transfer of a human gene.

The transformed phenotype of rat FE-8 cells transfected by an activated human HRAS gene was suppressed upon fusion with normal cells. An experimental approach was developed to identify and isolate a human gene capable of suppressing the transforming activity of the HRAS oncogene in FE-8 cells. Genom...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Schaefer, R, Iyer, J, Iten, E, Nirkko, A C
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1988
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC279819/
https://ncbi.nlm.nih.gov/pubmed/3125552
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