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Partial reversion of the transformed phenotype in HRAS-transfected tumorigenic cells by transfer of a human gene.
The transformed phenotype of rat FE-8 cells transfected by an activated human HRAS gene was suppressed upon fusion with normal cells. An experimental approach was developed to identify and isolate a human gene capable of suppressing the transforming activity of the HRAS oncogene in FE-8 cells. Genom...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279819/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3125552/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.5.1590 |
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