Rac1 and Cdc42 are regulators of HRas<sup>V12</sup>-transformation and angiogenic factors in human fibroblasts
<p>Abstract</p> <p>Background</p> <p>The activities of Rac1 and Cdc42 are essential for HRas-induced transformation of rodent fibroblasts. What is more, expression of constitutively activated mutants of Rac1 and/or Cdc42 is sufficient for their malignant transformation. The role for these two Rho GT...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BMC
2010-01-01
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| Collection: | BMC Cancer |
| Accès en ligne: | http://www.biomedcentral.com/1471-2407/10/13 |
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