APP gene family: unique age-associated changes in splicing of Alzheimer's βA4-amyloid protein precursor

The βA4-amyloid protein precursor (APP) is a transmembrane glycoprotein that is the source of the characteristic βA4-amyloid deposits of Alzheimer brains. It exists in eight isoforms generated by alternative splicing of exons 7, 8 and 15, of which the L-APP mRNAs lacking exon 15 are significantly ex...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Rupert Sandbrink, Colin L. Masters, Konrad Beyreuther
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 1994-11-01
Edice:	Neurobiology of Disease
Témata:	Alzheimer's disease APP gene family βA4-amyloid protein precursor amyloid precursor-like protein alternative splicing age-association of isoform expression
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S0969996184700039
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!