APP gene family: unique age-associated changes in splicing of Alzheimer's βA4-amyloid protein precursor
The βA4-amyloid protein precursor (APP) is a transmembrane glycoprotein that is the source of the characteristic βA4-amyloid deposits of Alzheimer brains. It exists in eight isoforms generated by alternative splicing of exons 7, 8 and 15, of which the L-APP mRNAs lacking exon 15 are significantly ex...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
1994-11-01
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| Seri Bilgileri: | Neurobiology of Disease |
| Konular: | |
| Online Erişim: | http://www.sciencedirect.com/science/article/pii/S0969996184700039 |
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