Amyloid-β Precursor Protein APP Down-Regulation Alters Actin Cytoskeleton-Interacting Proteins in Endothelial Cells

The amyloid-β precursor protein (APP) is a ubiquitous membrane protein often associated with Alzheimer’s disease (AD) and cerebral amyloid angiopathy (CAA). Despite its role in the development of the pathogenesis, APP exerts several physiological roles that have been mainly investigated in neuronal...

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Detalhes bibliográficos

Principais autores:	Emma Ristori, Vittoria Cicaloni, Laura Salvini, Laura Tinti, Cristina Tinti, Michael Simons, Federico Corti, Sandra Donnini, Marina Ziche
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-11-01
coleção:	Cells
Assuntos:	amyloid-β precursor protein APP vascular APP endothelial homeostasis actin cytoskeleton-interacting proteins integrins
Acesso em linha:	https://www.mdpi.com/2073-4409/9/11/2506
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