Induction of a Mesenchymal Expression Program in Lung Epithelial Cells by Wingless Protein (Wnt)/β-Catenin Requires the Presence of c-Jun N-Terminal Kinase–1 (JNK1)

Por van der Velden, Jos L. J., Guala, Amy S., Leggett, Susan E., Sluimer, Jasper, Badura, Elsbeth C. H. L., Janssen-Heininger, Yvonne M. W.
Publicado em 2012

Absence of c-Jun NH(2)-terminal kinase 1 protects against house dust mite-induced pulmonary remodeling but not airway hyperresponsiveness and inflammation

Por van der Velden, Jos L. J., Hoffman, Sidra M., Alcorn, John F., Tully, Jane E., Chapman, David G., Lahue, Karolyn G., Guala, Amy S., Lundblad, Lennart K. A., Aliyeva, Minara, Daphtary, Nirav, Irvin, Charles G., Janssen-Heininger, Yvonne M. W.
Publicado em 2014

Genetic ablation of glutaredoxin-1 causes enhanced resolution of airways hyperresponsiveness and mucus metaplasia in mice with allergic airways disease

Por Hoffman, Sidra M., Tully, Jane E., Lahue, Karolyn G., Anathy, Vikas, Nolin, James D., Guala, Amy S., van der Velden, Jos. L. J., Ho, Ye-Shih, Aliyeva, Minara, Daphtary, Nirav, Lundblad, Lennart K. A., Irvin, Charles G., Janssen-Heininger, Yvonne M. W.
Publicado em 2012

Glutathione S-transferase pi modulates NF-κB activation and pro-inflammatory responses in lung epithelial cells

Por Jones, Jane T., Qian, Xi, van der Velden, Jos L.J., Chia, Shi Biao, McMillan, David H., Flemer, Stevenson, Hoffman, Sidra M., Lahue, Karolyn G., Schneider, Robert W., Nolin, James D., Anathy, Vikas, van der Vliet, Albert, Townsend, Danyelle M., Tew, Kenneth D., Janssen-Heininger, Yvonne M.W.
Publicado no Redox Biol (2016)

JNK inhibition reduces lung remodeling and pulmonary fibrotic systemic markers

Por van der Velden, Jos L. J., Ye, Ying, Nolin, James D., Hoffman, Sidra M., Chapman, David G., Lahue, Karolyn G., Abdalla, Sarah, Chen, Peng, Liu, Yong, Bennett, Brydon, Khalil, Nasreen, Sutherland, Donna, Smith, William, Horan, Gerald, Assaf, Mahmoud, Horowitz, Zebulun, Chopra, Rajesh, Stevens, Randall M., Palmisano, Maria, Janssen-Heininger, Yvonne M. W., Schafer, Peter H.
Publicado no Clin Transl Med (2016)

Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π

Por McMillan, David H., van der Velden, Jos L.J., Lahue, Karolyn G., Qian, Xi, Schneider, Robert W., Iberg, Martina S., Nolin, James D., Abdalla, Sarah, Casey, Dylan T., Tew, Kenneth D., Townsend, Danyelle M., Henderson, Colin J., Wolf, C. Roland, Butnor, Kelly J., Taatjes, Douglas J., Budd, Ralph C., Irvin, Charles G., van der Vliet, Albert, Flemer, Stevenson, Anathy, Vikas, Janssen-Heininger, Yvonne M.W.
Publicado no JCI Insight (2016)