Induction of a Mesenchymal Expression Program in Lung Epithelial Cells by Wingless Protein (Wnt)/β-Catenin Requires the Presence of c-Jun N-Terminal Kinase–1 (JNK1)

Recent studies suggest the importance of the transition of airway epithelial cells (EMT) in pulmonary fibrosis, and also indicate a role for Wingless protein (Wnt)/β-catenin signaling in idiopathic pulmonary fibrosis. We investigated the possible role of the Wnt signaling pathway in inducing EMT in...

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Main Authors: van der Velden, Jos L. J., Guala, Amy S., Leggett, Susan E., Sluimer, Jasper, Badura, Elsbeth C. H. L., Janssen-Heininger, Yvonne M. W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488690/
https://ncbi.nlm.nih.gov/pubmed/22461429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0297OC
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