Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients

Por Forster, Victoria J., van Delft, Frederik W., Baird, Susan F., Mair, Shona, Skinner, Roderick, Halsey, Christina
Publicado no Cancer Chemother Pharmacol (2016)

CB-18 INTERROGATION OF SUB-CLONAL GENETIC DIVERSITY OF HUMAN GBM REVEALS GENETIC HETEROGENEITY IN TUMOUR-PROPAGATING CELLS, WHICH DISPLAY VARIABLE COMPETITIVE CAPACITY FOR TUMOUR P...

Por Watts, Colin, Piccirillo, Sara, Kearney, Lyndal, Potter, Nicola, van Delft, Frederik, Coleman, Sue, Lillis, Suzanne, Carnicer, Maria-Jose, Greaves, Mel
Publicado em 2014

Genetic and Functional Diversity of Propagating Cells in Glioblastoma

Por Piccirillo, Sara G.M., Colman, Sue, Potter, Nicola E., van Delft, Frederik W., Lillis, Suzanne, Carnicer, Maria-Jose, Kearney, Lyndal, Watts, Colin, Greaves, Mel
Publicado no Stem Cell Reports (2014)

ATPS-93 CHEMO-NAÏVE GLIOBLASTOMA PATIENTS CONTAIN GENETICALLY HETEROGENEOUS SUB-CLONES CAPABLE OF TUMOUR PROPAGATION AND SPATIALLY HETEROGENEOUS DRUG-RESISTANT CELL POPULATIONS

Por Watts, Colin, Piccirillo, Sara, Colman, Sue, Potter, Nicola, van Delft, Frederik, Lillis, Suzanne, Carnicer, Maria-Jose, Kearney, Lyndal, Francis, Nicola-Jane, Venkitaraman, Ashok, Greaves, Mel
Publicado no Neuro Oncol (2015)

Developmental origins and impact of BCR-ABL1 fusion and IKZF1 deletions in monozygotic twins with Ph(+) acute lymphoblastic leukemia

Por Cazzaniga, Giovanni, van Delft, Frederik W., Lo Nigro, Luca, Ford, Anthony M., Score, Joannah, Iacobucci, Ilaria, Mirabile, Elena, Taj, Mary, Colman, Susan M., Biondi, Andrea, Greaves, Mel
Publicado em 2011

Immunologically silent cancer clone transmission from mother to offspring

Por Isoda, Takeshi, Ford, Anthony M., Tomizawa, Daisuke, van Delft, Frederik W., De Castro, David Gonzalez, Mitsuiki, Norkio, Score, Joannah, Taki, Tomohiko, Morio, Tomohiro, Takagi, Masatoshi, Saji, Hiroh, Greaves, Mel, Mizutani, Shuki
Publicado em 2009

Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

Por Strefford, Jon C., van Delft, Frederik W., Robinson, Hazel M., Worley, Helen, Yiannikouris, Olga, Selzer, Rebecca, Richmond, Todd, Hann, Ian, Bellotti, Tony, Raghavan, Manoj, Young, Bryan D., Saha, Vaskar, Harrison, Christine J.
Publicado em 2006

Modeling the evolution of ETV6-RUNX1-induced B-cell precursor acute lymphoblastic leukemia in mice

Por van der Weyden, Louise, Giotopoulos, George, Rust, Alistair G., Matheson, Louise S., van Delft, Frederik W., Kong, Jun, Corcoran, Anne E., Greaves, Mel F., Mullighan, Charles G., Huntly, Brian J., Adams, David J.
Publicado em 2011

Distinctive genotypes in infants with T‐cell acute lymphoblastic leukaemia

Por Mansur, Marcela B., van Delft, Frederik W., Colman, Susan M., Furness, Caroline L., Gibson, Jane, Emerenciano, Mariana, Kempski, Helena, Clappier, Emmanuelle, Cave, Hélène, Soulier, Jean, Pombo‐de‐Oliveira, Maria S., Greaves, Mel, Ford, Anthony M.
Publicado no Br J Haematol (2015)

A dyad of lymphoblastic lysosomal cysteine proteases degrades the antileukemic drug l-asparaginase

Por Patel, Naina, Krishnan, Shekhar, Offman, Marc N., Krol, Marcin, Moss, Catherine X., Leighton, Carly, van Delft, Frederik W., Holland, Mark, Liu, JiZhong, Alexander, Seema, Dempsey, Clare, Ariffin, Hany, Essink, Monika, Eden, Tim O.B., Watts, Colin, Bates, Paul A., Saha, Vaskar
Publicado em 2009

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia

Por Papaemmanuil, Elli, Rapado, Inmaculada, Li, Yilong, Potter, Nicola E, Wedge, David C, Tubio, Jose, Alexandrov, Ludmil B, Van Loo, Peter, Cooke, Susanna L, Marshall, John, Martincorena, Inigo, Hinton, Jonathan, Gundem, Gunes, van Delft, Frederik W, Nik-Zainal, Serena, Jones, David R, Ramakrishna, Manasa, Titley, Ian, Stebbings, Lucy, Leroy, Catherine, Menzies, Andrew, Gamble, John, Robinson, Ben, Mudie, Laura, Raine, Keiran, O’Meara, Sarah, Teague, Jon W, Butler, Adam P, Cazzaniga, Giovanni, Biondi, Andrea, Zuna, Jan, Kempski, Helena, Muschen, Markus, Ford, Anthony M, Stratton, Michael R, Greaves, Mel, Campbell, Peter J
Publicado em 2014