Genetic Determinants of Breast Cancer Risk in Childhood Cancer Survivors

par Meier, Magda, Orr, Nick
Publié dans J Natl Cancer Inst (2017)

TINF2, a Component of the Shelterin Telomere Protection Complex, Is Mutated in Dyskeratosis Congenita

par Savage, Sharon A., Giri, Neelam, Baerlocher, Gabriela M., Orr, Nick, Lansdorp, Peter M., Alter, Blanche P.
Publié 2008

Estimating causal effects of genetic risk variants for breast cancer using marker data from bilateral and familial cases

par Dudbridge, Frank, Fletcher, Olivia, Walker, Kate, Johnson, Nichola, Orr, Nick, dos Santos Silva, Isabel, Peto, Julian
Publié 2011

Neovascular Age-Related Macular Degeneration Risk Based on CFH, LOC387715/HTRA1, and Smoking

par Hughes, Anne E, Orr, Nick, Patterson, Chris, Esfandiary, Hossein, Hogg, Ruth, McConnell, Vivienne, Silvestri, Giuliana, Chakravarthy, Usha
Publié 2007

A Genome Scan for Positive Selection in Thoroughbred Horses

par Gu, Jingjing, Orr, Nick, Park, Stephen D., Katz, Lisa M., Sulimova, Galina, MacHugh, David E., Hill, Emmeline W.
Publié 2009

Genetic Variants at Chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 Influence the Risk of Breast Cancer in Men

par Orr, Nick, Cooke, Rosie, Jones, Michael, Fletcher, Olivia, Dudbridge, Frank, Chilcott-Burns, Sarah, Tomczyk, Katarzyna, Broderick, Peter, Houlston, Richard, Ashworth, Alan, Swerdlow, Anthony
Publié 2011

A Sequence Polymorphism in MSTN Predicts Sprinting Ability and Racing Stamina in Thoroughbred Horses

par Hill, Emmeline W., Gu, Jingjing, Eivers, Suzanne S., Fonseca, Rita G., McGivney, Beatrice A., Govindarajan, Preethi, Orr, Nick, Katz, Lisa M., MacHugh, David
Publié 2010

Correction: A Sequence Polymorphism in MSTN Predicts Sprinting Ability and Racing Stamina in Thoroughbred Horses

par Hill, Emmeline W., Gu, Jingjing, Eivers, Suzanne S., Fonseca, Rita G., McGivney, Beatrice A., Govindarajan, Preethi, Orr, Nick, Katz, Lisa M., MacHugh, David E.
Publié 2010

MUTATIONS AND POLYMORPHISMS IN HEMOGLOBIN GENES AND THE RISK OF PULMONARY HYPERTENSION AND DEATH IN SICKLE CELL DISEASE

par Taylor, James G., Ackah, Diana, Cobb, Crystal, Orr, Nick, Percy, Melanie J., Sachdev, Vandana, Machado, Roberto, Castro, Oswaldo, Kato, Gregory J., Chanock, Stephen J., Gladwin, Mark T.
Publié 2008

Population-based estimates of the prevalence of FMR1 expansion mutations in women with early menopause and primary ovarian insufficiency

par Murray, Anna, Schoemaker, Minouk J., Bennett, Claire E., Ennis, Sarah, Macpherson, James N., Jones, Michael, Morris, Danielle H., Orr, Nick, Ashworth, Alan, Jacobs, Patricia A., Swerdlow, Anthony J.
Publié 2014

Comparative Validation of Breast Cancer Risk Prediction Models and Projections for Future Risk Stratification

par Pal Choudhury, Parichoy, Wilcox, Amber N, Brook, Mark N, Zhang, Yan, Ahearn, Thomas, Orr, Nick, Coulson, Penny, Schoemaker, Minouk J, Jones, Michael E, Gail, Mitchell H, Swerdlow, Anthony J, Chatterjee, Nilanjan, Garcia-Closas, Montserrat
Publié dans J Natl Cancer Inst (2019)

Cytochrome P450 allele CYP3A7*1C associates with adverse outcomes in chronic lymphocytic leukemia, breast and lung cancer

par Johnson, Nichola, De Ieso, Paolo, Migliorini, Gabriele, Orr, Nick, Broderick, Peter, Catovsky, Daniel, Matakidou, Athena, Eisen, Timothy, Goldsmith, Christy, Dudbridge, Frank, Peto, Julian, dos-Santos-Silva, Isabel, Ashworth, Alan, Ross, Gillian, Houlston, Richard S, Fletcher, Olivia
Publié dans Cancer Res (2016)

Common Variation in Genes Related to Innate Immunity and Risk of Adult Glioma

par Rajaraman, Preetha, Brenner, Alina V., Butler, Mary Ann, Wang, Sophia S., Pfeiffer, Ruth M., Ruder, Avima M., Linet, Martha S., Yeager, Meredith, Wang, Zhaoming, Orr, Nick, Fine, Howard A., Kwon, Deukwoo, Thomas, Gilles, Rothman, Nathaniel, Inskip, Peter D., Chanock, Stephen J.
Publié 2009

Capture Hi-C identifies putative target genes at 33 breast cancer risk loci

par Baxter, Joseph S., Leavy, Olivia C., Dryden, Nicola H., Maguire, Sarah, Johnson, Nichola, Fedele, Vita, Simigdala, Nikiana, Martin, Lesley-Ann, Andrews, Simon, Wingett, Steven W., Assiotis, Ioannis, Fenwick, Kerry, Chauhan, Ritika, Rust, Alistair G., Orr, Nick, Dudbridge, Frank, Haider, Syed, Fletcher, Olivia
Publié dans Nat Commun (2018)

Validation of loci at 2q14.2 and 15q21.3 as risk factors for testicular cancer

par Loveday, Chey, Litchfield, Kevin, Levy, Max, Holroyd, Amy, Broderick, Peter, Kote-Jarai, Zsofia, Dunning, Alison M, Muir, Kenneth, Peto, Julian, Eeles, Rosalind, Easton, Douglas F, Dudakia, Darshna, Orr, Nick, Pashayan, Nora, Reid, Alison, Huddart, Robert A, Houlston, Richard S, Turnbull, Clare
Publié dans Oncotarget (2017)

Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C

par Dryden, Nicola H., Broome, Laura R., Dudbridge, Frank, Johnson, Nichola, Orr, Nick, Schoenfelder, Stefan, Nagano, Takashi, Andrews, Simon, Wingett, Steven, Kozarewa, Iwanka, Assiotis, Ioannis, Fenwick, Kerry, Maguire, Sarah L., Campbell, James, Natrajan, Rachael, Lambros, Maryou, Perrakis, Eleni, Ashworth, Alan, Fraser, Peter, Fletcher, Olivia
Publié 2014

Comprehensive resequence analysis of a 136 kb region of human chromosome 8q24 associated with prostate and colon cancers

par Yeager, Meredith, Xiao, Nianqing, Hayes, Richard B., Bouffard, Pascal, Desany, Brian, Burdett, Laura, Orr, Nick, Matthews, Casey, Qi, Liqun, Crenshaw, Andrew, Markovic, Zdenek, Fredrikson, Karin M., Jacobs, Kevin B., Amundadottir, Laufey, Jarvie, Thomas P., Hunter, David J., Hoover, Robert, Thomas, Gilles, Harkins, Timothy T., Chanock, Stephen J.
Publié 2008

Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma

par Sud, Amit, Thomsen, Hauke, Orlando, Giulia, Försti, Asta, Law, Philip J., Broderick, Peter, Cooke, Rosie, Hariri, Fadi, Pastinen, Tomi, Easton, Douglas F., Pharoah, Paul D. P., Dunning, Alison M., Peto, Julian, Canzian, Federico, Eeles, Rosalind, Kote-Jarai, ZSofia, Muir, Kenneth, Pashayan, Nora, Campa, Daniele, Hoffmann, Per, Nöthen, Markus M., Jöckel, Karl-Heinz, von Strandmann, Elke Pogge, Swerdlow, Anthony J., Engert, Andreas, Orr, Nick, Hemminki, Kari, Houlston, Richard S.
Publié dans Blood (2018)

Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor

par Litchfield, Kevin, Levy, Max, Orlando, Giulia, Loveday, Chey, Law, Philip, Migliorini, Gabriele, Holroyd, Amy, Broderick, Peter, Karlsson, Robert, Haugen, Trine B, Kristiansen, Wenche, Nsengimana, Jérémie, Fenwick, Kerry, Assiotis, Ioannis, Kote-Jarai, ZSofia, Dunning, Alison M., Muir, Kenneth, Peto, Julian, Eeles, Rosalind, Easton, Douglas F, Dudakia, Darshna, Orr, Nick, Pashayan, Nora, Bishop, D. Timothy, Reid, Alison, Huddart, Robert A, Shipley, Janet, Grotmol, Tom, Wiklund, Fredrik, Houlston, Richard S, Turnbull, Clare
Publié dans Nat Genet (2017)

A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer

par Hunter, David J., Kraft, Peter, Jacobs, Kevin B., Cox, David G., Yeager, Meredith, Hankinson, Susan E., Wacholder, Sholom, Wang, Zhaoming, Welch, Robert, Hutchinson, Amy, Yu, Kai, Chatterjee, Nilanjan, Orr, Nick, Willett, Walter C., Colditz, Graham A., Ziegler, Regina G., Berg, Christine D., Buys, Saundra S., McCarty, Catherine A., Feigelson, Heather Spencer, Calle, Eugenia E., Thun, Michael J., Hayes, Richard B., Tucker, Margaret, Gerhard, Daniela S., Fraumeni, Joseph F., Hoover, Robert N., Thomas, Gilles, Chanock, Stephen J
Publié 2007