MUTATIONS AND POLYMORPHISMS IN HEMOGLOBIN GENES AND THE RISK OF PULMONARY HYPERTENSION AND DEATH IN SICKLE CELL DISEASE

Pulmonary hypertension is a common complication of sickle cell disease (SCD) and a risk factor for early death. Hemolysis may participate in its pathogenesis by limiting nitric oxide (NO) bioavailability and producing vasculopathy. We hypothesized that hemoglobin mutations that diminish hemolysis in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Taylor, James G., Ackah, Diana, Cobb, Crystal, Orr, Nick, Percy, Melanie J., Sachdev, Vandana, Machado, Roberto, Castro, Oswaldo, Kato, Gregory J., Chanock, Stephen J., Gladwin, Mark T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509176/
https://ncbi.nlm.nih.gov/pubmed/17724704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.21035
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg