Neovascular Age-Related Macular Degeneration Risk Based on CFH, LOC387715/HTRA1, and Smoking

BACKGROUND: Age-related macular degeneration (AMD) is the major cause of blindness in the elderly. Those with the neovascular end-stage of disease have irreversible loss of central vision. AMD is a complex disorder in which genetic and environmental factors play a role. Polymorphisms in the compleme...

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Detalhes bibliográficos
Main Authors: Hughes, Anne E, Orr, Nick, Patterson, Chris, Esfandiary, Hossein, Hogg, Ruth, McConnell, Vivienne, Silvestri, Giuliana, Chakravarthy, Usha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222948/
https://ncbi.nlm.nih.gov/pubmed/18162041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040355
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