Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor

Genome-wide association studies (GWAS) have transformed our understanding of testicular germ cell tumour (TGCT) susceptibility but much of the heritability remains unexplained. Here we report a new GWAS, a meta-analysis with previous GWAS and a replication series, totalling 7,319 TGCT cases and 23,0...

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Publicat a:Nat Genet
Autors principals: Litchfield, Kevin, Levy, Max, Orlando, Giulia, Loveday, Chey, Law, Philip, Migliorini, Gabriele, Holroyd, Amy, Broderick, Peter, Karlsson, Robert, Haugen, Trine B, Kristiansen, Wenche, Nsengimana, Jérémie, Fenwick, Kerry, Assiotis, Ioannis, Kote-Jarai, ZSofia, Dunning, Alison M., Muir, Kenneth, Peto, Julian, Eeles, Rosalind, Easton, Douglas F, Dudakia, Darshna, Orr, Nick, Pashayan, Nora, Bishop, D. Timothy, Reid, Alison, Huddart, Robert A, Shipley, Janet, Grotmol, Tom, Wiklund, Fredrik, Houlston, Richard S, Turnbull, Clare
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016736/
https://ncbi.nlm.nih.gov/pubmed/28604728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3896
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