Fibrinogen-Related Proteins in Tissue Repair: How a Unique Domain with a Common Structure Controls Diverse Aspects of Wound Healing

door Zuliani-Alvarez, Lorena, Midwood, Kim S.
Gepubliceerd in Adv Wound Care (New Rochelle) (2015)

Identifying a nuclear passport for HIV

door Zuliani-Alvarez, Lorena, Towers, Greg J
Gepubliceerd in eLife (2019)

Screening for Novel Endogenous Inflammatory Stimuli Using the Secreted Embryonic Alkaline Phosphatase NF-κB Reporter Assay

door Zuliani-Alvarez, Lorena, Piccinini, Anna M., Midwood, Kim S
Gepubliceerd in Bio Protoc (2017)

TLR4-Mediated Pathway Triggers Interferon-Independent G0 Arrest and Antiviral SAMHD1 Activity in Macrophages

door Mlcochova, Petra, Winstone, Helena, Zuliani-Alvarez, Lorena, Gupta, Ravindra K.
Gepubliceerd in Cell Rep (2020)

Distinct microenvironmental cues stimulate divergent TLR4-mediated signaling pathways in macrophages

door Piccinini, Anna M., Zuliani-Alvarez, Lorena, Lim, Jenny M. P., Midwood, Kim S.
Gepubliceerd in Sci Signal (2016)

Disrupting HIV‐1 capsid formation causes cGAS sensing of viral DNA

door Sumner, Rebecca P, Harrison, Lauren, Touizer, Emma, Peacock, Thomas P, Spencer, Matthew, Zuliani‐Alvarez, Lorena, Towers, Greg J
Gepubliceerd in EMBO J (2020)

Mapping tenascin-C interaction with toll-like receptor 4 reveals a new subset of endogenous inflammatory triggers

door Zuliani-Alvarez, Lorena, Marzeda, Anna M., Deligne, Claire, Schwenzer, Anja, McCann, Fiona E., Marsden, Brian D., Piccinini, Anna M., Midwood, Kim S.
Gepubliceerd in Nat Commun (2017)

SARS‐CoV‐2 sensing by RIG‐I and MDA5 links epithelial infection to macrophage inflammation

door Thorne, Lucy G, Reuschl, Ann‐Kathrin, Zuliani‐Alvarez, Lorena, Whelan, Matthew V X, Turner, Jane, Noursadeghi, Mahdad, Jolly, Clare, Towers, Greg J
Gepubliceerd in EMBO J (2021)

Tenascin C upregulates interleukin-6 expression in human cardiac myofibroblasts via toll-like receptor 4

door Maqbool, Azhar, Spary, Emma J, Manfield, Iain W, Ruhmann, Michaela, Zuliani-Alvarez, Lorena, Gamboa-Esteves, Filomena O, Porter, Karen E, Drinkhill, Mark J, Midwood, Kim S, Turner, Neil A
Gepubliceerd in World J Cardiol (2016)

HIV-1 Vpr antagonizes innate immune activation by targeting karyopherin-mediated NF-κB/IRF3 nuclear transport

door Khan, Hataf, Sumner, Rebecca P, Rasaiyaah, Jane, Tan, Choon Ping, Rodriguez-Plata, Maria Teresa, Van Tulleken, Chris, Fink, Douglas, Zuliani-Alvarez, Lorena, Thorne, Lucy, Stirling, David, Milne, Richard SB, Towers, Greg J
Gepubliceerd in eLife (2020)

Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant

door Reuschl, Ann-Kathrin, Thorne, Lucy G., Zuliani-Alvarez, Lorena, Bouhaddou, Mehdi, Obernier, Kirsten, Hiatt, Joseph, Soucheray, Margaret, Turner, Jane, Fabius, Jacqueline M., Nguyen, Gina T., Swaney, Danielle L., Rosales, Romel, White, Kris M., Avilés, Pablo, Kirby, Ilsa T., Melnyk, James E., Shi, Ying, Zhang, Ziyang, Shokat, Kevan M., García-Sastre, Adolfo, Jolly, Clare, Towers, Gregory J., Krogan, Nevan J.
Gepubliceerd in bioRxiv (2021)

Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant

door Thorne, Lucy G, Bouhaddou, Mehdi, Reuschl, Ann-Kathrin, Zuliani-Alvarez, Lorena, Polacco, Ben, Pelin, Adrian, Batra, Jyoti, Whelan, Matthew V.X., Ummadi, Manisha, Rojc, Ajda, Turner, Jane, Obernier, Kirsten, Braberg, Hannes, Soucheray, Margaret, Richards, Alicia, Chen, Kuei-Ho, Harjai, Bhavya, Memon, Danish, Hosmillo, Myra, Hiatt, Joseph, Jahun, Aminu, Goodfellow, Ian G., Fabius, Jacqueline M., Shokat, Kevan, Jura, Natalia, Verba, Klim, Noursadeghi, Mahdad, Beltrao, Pedro, Swaney, Danielle L., Garcia-Sastre, Adolfo, Jolly, Clare, Towers, Greg J., Krogan, Nevan J.
Gepubliceerd in bioRxiv (2021)

Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization

door Varona, José F., Landete, Pedro, Lopez-Martin, Jose A., Estrada, Vicente, Paredes, Roger, Guisado-Vasco, Pablo, de Orueta, Lucía Fernández, Torralba, Miguel, Fortún, Jesús, Vates, Roberto, Barberán, José, Clotet, Bonaventura, Ancochea, Julio, Carnevali, Daniel, Cabello, Noemí, Porras, Lourdes, Gijón, Paloma, Monereo, Alfonso, Abad, Daniel, Zúñiga, Sonia, Sola, Isabel, Rodon, Jordi, Izquierdo-Useros, Nuria, Fudio, Salvador, Pontes, María José, de Rivas, Beatriz, Girón de Velasco, Patricia, Sopesén, Belén, Nieto, Antonio, Gómez, Javier, Avilés, Pablo, Lubomirov, Rubin, White, Kris M., Rosales, Romel, Yildiz, Soner, Reuschl, Ann-Kathrin, Thorne, Lucy G., Jolly, Clare, Towers, Greg J., Zuliani-Alvarez, Lorena, Bouhaddou, Mehdi, Obernier, Kirsten, Enjuanes, Luis, Fernández-Sousa, Jose M., Krogan, Nevan J., Jimeno, José M., García-Sastre, Adolfo
Gepubliceerd in medRxiv (2021)

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

door Gupta, Meghna, Azumaya, Caleigh M., Moritz, Michelle, Pourmal, Sergei, Diallo, Amy, Merz, Gregory E., Jang, Gwendolyn, Bouhaddou, Mehdi, Fossati, Andrea, Brilot, Axel F., Diwanji, Devan, Hernandez, Evelyn, Herrera, Nadia, Kratochvil, Huong T., Lam, Victor L., Li, Fei, Li, Yang, Nguyen, Henry C., Nowotny, Carlos, Owens, Tristan W., Peters, Jessica K., Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Young, Iris D., Yu, Zanlin, Asarnow, Daniel, Billesbølle, Christian, Campbell, Melody G., Chen, Jen, Chen, Kuei-Ho, Chio, Un Seng, Dickinson, Miles Sasha, Doan, Loan, Jin, Mingliang, Kim, Kate, Li, Junrui, Li, Yen-Li, Linossi, Edmond, Liu, Yanxin, Lo, Megan, Lopez, Jocelyne, Lopez, Kyle E., Mancino, Adamo, Moss, Frank R., Paul, Michael D., Pawar, Komal Ishwar, Pelin, Adrian, Pospiech, Thomas H., Puchades, Cristina, Remesh, Soumya Govinda, Safari, Maliheh, Schaefer, Kaitlin, Sun, Ming, Tabios, Mariano C, Thwin, Aye C., Titus, Erron W., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Zhang, Kaihua, Zhang, Yang, Zhao, Jianhua, Zhou, Fengbo, Zhou, Yuan, Zuliani-Alvarez, Lorena, Agard, David A, Cheng, Yifan, Fraser, James S, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M, Swaney, Danielle L, Krogan, Nevan J, Frost, Adam, Rosenberg, Oren S, Verba, Kliment A
Gepubliceerd in bioRxiv (2021)

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

door Gupta, Meghna, Azumaya, Caleigh M., Moritz, Michelle, Pourmal, Sergei, Diallo, Amy, Merz, Gregory E., Jang, Gwendolyn, Bouhaddou, Mehdi, Fossati, Andrea, Brilot, Axel F., Diwanji, Devan, Hernandez, Evelyn, Herrera, Nadia, Kratochvil, Huong T., Lam, Victor L., Li, Fei, Li, Yang, Nguyen, Henry C., Nowotny, Carlos, Owens, Tristan W., Peters, Jessica K., Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Young, Iris D., Yu, Zanlin, Asarnow, Daniel, Billesbølle, Christian, Campbell, Melody G., Chen, Jen, Chen, Kuei-Ho, Chio, Un Seng, Dickinson, Miles Sasha, Doan, Loan, Jin, Mingliang, Kim, Kate, Li, Junrui, Li, Yen-Li, Linossi, Edmond, Liu, Yanxin, Lo, Megan, Lopez, Jocelyne, Lopez, Kyle E., Mancino, Adamo, Moss, Frank R., Paul, Michael D., Pawar, Komal Ishwar, Pelin, Adrian, Pospiech, Thomas H., Puchades, Cristina, Remesh, Soumya Govinda, Safari, Maliheh, Schaefer, Kaitlin, Sun, Ming, Tabios, Mariano C, Thwin, Aye C., Titus, Erron W., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Zhang, Kaihua, Zhang, Yang, Zhao, Jianhua, Zhou, Fengbo, Zhou, Yuan, Zuliani-Alvarez, Lorena, Agard, David A, Cheng, Yifan, Fraser, James S, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M, Swaney, Danielle L, Krogan, Nevan J, Frost, Adam, Rosenberg, Oren S, Verba, Kliment A
Gepubliceerd in Res Sq (2021)