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Distinct microenvironmental cues stimulate divergent TLR4-mediated signaling pathways in macrophages

Macrophages exhibit a phenotypic plasticity that enables them to orchestrate specific immune responses to distinct threats. The microbial product lipopolysaccharide (LPS) and the extracellular matrix glycoprotein tenascin-C are released during bacterial infection and tissue injury, respectively, and...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Piccinini, Anna M., Zuliani-Alvarez, Lorena, Lim, Jenny M. P., Midwood, Kim S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338747/
https://ncbi.nlm.nih.gov/pubmed/27577261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaf3596
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