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Distinct microenvironmental cues stimulate divergent TLR4-mediated signaling pathways in macrophages
Macrophages exhibit a phenotypic plasticity that enables them to orchestrate specific immune responses to distinct threats. The microbial product lipopolysaccharide (LPS) and the extracellular matrix glycoprotein tenascin-C are released during bacterial infection and tissue injury, respectively, and...
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| Pubblicato in: | Sci Signal |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338747/ https://ncbi.nlm.nih.gov/pubmed/27577261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaf3596 |
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