Hsp90 and co-chaperones twist the functions of diverse client proteins

Por Zuehlke, Abbey, Johnson, Jill L.
Publicado em 2010

Clients Place Unique Functional Constraints on Hsp90

Por Zuehlke, Abbey D., Neckers, Len
Publicado no Trends Biochem Sci (2016)

Out with the old: Hsp90 finds amino acid residue more useful than co-chaperone protein

Por Zuehlke, Abbey D., Neckers, Leonard
Publicado no Microb Cell (2017)

Chaperoning the Chaperone: A Role for the Co-chaperone Cpr7 in Modulating Hsp90 Function in Saccharomyces cerevisiae

Por Zuehlke, Abbey D., Johnson, Jill L.
Publicado em 2012

Heat shock protein 90: its inhibition and function

Por Zuehlke, Abbey D., Moses, Michael A., Neckers, Len
Publicado no Philos Trans R Soc Lond B Biol Sci (2018)

Regulation and function of the human HSP90AA1 gene

Por Zuehlke, Abbey D., Beebe, Kristin, Neckers, Len, Prince, Thomas
Publicado no Gene (2015)

Interaction of Heat Shock Protein 90 and the Co-chaperone Cpr6 with Ura2, a Bifunctional Enzyme Required for Pyrimidine Biosynthesis

Por Zuehlke, Abbey D., Wren, Nicholas, Tenge, Victoria, Johnson, Jill L.
Publicado em 2013

The Hsp90 Cochaperones Cpr6, Cpr7, and Cns1 Interact with the Intact Ribosome

Por Tenge, Victoria R., Zuehlke, Abbey D., Shrestha, Neelima, Johnson, Jill L.
Publicado no Eukaryot Cell (2014)

Combined HSP90 and kinase inhibitor therapy: Insights from The Cancer Genome Atlas

Por Schwartz, Harvey, Scroggins, Brad, Zuehlke, Abbey, Kijima, Toshiki, Beebe, Kristin, Mishra, Alok, Neckers, Len, Prince, Thomas
Publicado no Cell Stress Chaperones (2015)

An Hsp90 co-chaperone protein in yeast is functionally replaced by site-specific posttranslational modification in humans

Por Zuehlke, Abbey D., Reidy, Michael, Lin, Coney, LaPointe, Paul, Alsomairy, Sarah, Lee, D. Joshua, Rivera-Marquez, Genesis M., Beebe, Kristin, Prince, Thomas, Lee, Sunmin, Trepel, Jane B., Xu, Wanping, Johnson, Jill, Masison, Daniel, Neckers, Len
Publicado no Nat Commun (2017)

Activation of Hsp90 enzymatic activity and conformational dynamics through rationally designed allosteric ligands

Por Sattin, Sara, Tao, Jiahui, Vettoretti, Gerolamo, Moroni, Elisabetta, Pennati, Marzia, Lopergolo, Alessia, Morelli, Laura, Bugatti, Antonella, Zuehlke, Abbey, Moses, Mike, Prince, Thomas, Kijima, Toshiki, Beebe, Kristin, Rusnati, Marco, Neckers, Len, Zaffaroni, Nadia, Agard, David A., Bernardi, Anna, Colombo, Giorgio
Publicado no Chemistry (2015)

Targeting the Hsp40/Hsp70 chaperone axis as a novel strategy to treat castration-resistant prostate cancer

Por Moses, Michael A., Kim, Yeong Sang, Rivera-Marquez, Genesis M., Oshima, Nobu, Watson, Matthew J., Beebe, Kristin E., Wells, Catherine, Lee, Sunmin, Zuehlke, Abbey D., Shao, Hao, Bingman, William E., Kumar, Vineet, Malhotra, Sanjay V., Weigel, Nancy L., Gestwicki, Jason E., Trepel, Jane B., Neckers, Leonard M.
Publicado no Cancer Res (2018)