Derivation of Diverse Hormone-Releasing Pituitary Cells from Human Pluripotent Stem Cells

Por Zimmer, Bastian, Piao, Jinghua, Ramnarine, Kiran, Tomishima, Mark J., Tabar, Viviane, Studer, Lorenz
Publicado no Stem Cell Reports (2016)

A MODULAR PLATFORM FOR DIFFERENTIATION OF HUMAN PSCS INTO ALL MAJOR ECTODERMAL LINEAGES

Por Tchieu, Jason, Zimmer, Bastian, Fattahi, Faranak, Amin, Sadaf, Zeltner, Nadja, Chen, Shuibing, Studer, Lorenz
Publicado no Cell Stem Cell (2017)

Evaluation of Developmental Toxicants and Signaling Pathways in a Functional Test Based on the Migration of Human Neural Crest Cells

Por Zimmer, Bastian, Lee, Gabsang, Balmer, Nina V, Meganathan, Kesavan, Sachinidis, Agapios, Studer, Lorenz, Leist, Marcel
Publicado em 2012

Specification of Functional Cranial Placode Derivatives from Human Pluripotent Stem Cells

Por Dincer, Zehra, Piao, Jinghua, Niu, Lei, Ganat, Yosif, Kriks, Sonja, Zimmer, Bastian, Shi, Song-Hai, Tabar, Viviane, Studer, Lorenz
Publicado em 2013

Extensive Transcriptional Regulation of Chromatin Modifiers during Human Neurodevelopment

Por Weng, Matthias K., Zimmer, Bastian, Pöltl, Dominik, Broeg, Marc P., Ivanova, Violeta, Gaspar, John A., Sachinidis, Agapios, Wüllner, Ullrich, Waldmann, Tanja, Leist, Marcel
Publicado em 2012

Capturing the biology of mild versus severe disease in a pluripotent stem cell-based model of Familial Dysautonomia

Por Zeltner, Nadja, Fattahi, Faranak, Dubois, Nicole C., Saurat, Nathalie, Lafaille, Fabien, Shang, Lei, Zimmer, Bastian, Tchieu, Jason, Soliman, Mohamed A., Lee, Gabsang, Casanova, Jean-Laurent, Studer, Lorenz
Publicado no Nat Med (2016)

DERIVING HUMAN ENS LINEAGES FOR CELL THERAPY AND DRUG DISCOVERY IN HIRSCHSPRUNG'S DISEASE

Por Fattahi, Faranak, Steinbeck, Julius A, Kriks, Sonja, Tchieu, Jason, Zimmer, Bastian, Kishinevsky, Sarah, Zeltner, Nadja, Mica, Yvonne, El-Nachef, Wael, Zhao, Huiyong, de Stanchina, Elisa, Gershon, Michael D., Grikscheit, Tracy C., Chen, Shuibing, Studer, Lorenz
Publicado no Nature (2016)

Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use

Por Aschner, Michael, Ceccatelli, Sandra, Daneshian, Mardas, Fritsche, Ellen, Hasiwa, Nina, Hartung, Thomas, Hogberg, Helena T., Leist, Marcel, Li, Abby, Mundy, William R., Padilla, Stephanie, Piersma, Aldert H., Bal-Price, Anna, Seiler, Andrea, Westerink, Remco H., Zimmer, Bastian, Lein, Pamela J.
Publicado no ALTEX (2016)

Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infection

Por Zimmer, Bastian, Ewaleifoh, Osefame, Harschnitz, Oliver, Lee, Yoon-Seung, Peneau, Camille, McAlpine, Jessica L., Liu, Becky, Tchieu, Jason, Steinbeck, Julius A., Lafaille, Fabien, Volpi, Stefano, Notarangelo, Luigi D., Casanova, Jean-Laurent, Zhang, Shen-Ying, Smith, Gregory A., Studer, Lorenz
Publicado no Proc Natl Acad Sci U S A (2018)

Combined small-molecule inhibition accelerates the derivation of functional, early-born, cortical neurons from human pluripotent stem cells

Por Qi, Yuchen, Zhang, Xin-Jun, Renier, Nicolas, Wu, Zhuhao, Atkin, Talia, Sun, Ziyi, Ozair, M. Zeeshan, Tchieu, Jason, Zimmer, Bastian, Fattahi, Faranak, Ganat, Yosif, Azevedo, Ricardo, Zeltner, Nadja, Brivanlou, Ali H., Karayiorgou, Maria, Gogos, Joseph, Tomishima, Mark, Tessier-Lavigne, Marc, Shi, Song-Hai, Studer, Lorenz
Publicado no Nat Biotechnol (2017)

HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons

Por Kishinevsky, Sarah, Wang, Tai, Rodina, Anna, Chung, Sun Young, Xu, Chao, Philip, John, Taldone, Tony, Joshi, Suhasini, Alpaugh, Mary L., Bolaender, Alexander, Gutbier, Simon, Sandhu, Davinder, Fattahi, Faranak, Zimmer, Bastian, Shah, Smit K., Chang, Elizabeth, Inda, Carmen, Koren, John, Saurat, Nathalie G., Leist, Marcel, Gross, Steven S., Seshan, Venkatraman E., Klein, Christine, Tomishima, Mark J., Erdjument-Bromage, Hediye, Neubert, Thomas A., Henrickson, Ronald C., Chiosis, Gabriela, Studer, Lorenz
Publicado no Nat Commun (2018)

Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis

Por Lafaille, Fabien G., Harschnitz, Oliver, Lee, Yoon Seung, Zhang, Peng, Hasek, Mary L., Kerner, Gaspard, Itan, Yuval, Ewaleifoh, Osefame, Rapaport, Franck, Carlile, Thomas M., Carter-Timofte, Madalina E., Paquet, Dominik, Dobbs, Kerry, Zimmer, Bastian, Gao, Daxing, Rojas-Duran, Maria F., Kwart, Dylan, Rattina, Vimel, Ciancanelli, Michael J., McAlpine, Jessica L., Lorenzo, Lazaro, Boucherit, Soraya, Rozenberg, Flore, Halwani, Rabih, Henry, Benoit, Amenzoui, Naima, Alsum, Zobaida, Marques, Laura, Church, Joseph A., Al-Muhsen, Saleh, Tardieu, Marc, Bousfiha, Ahmed Aziz, Paludan, Søren R., Mogensen, Trine Hyrup, Quintana-Murci, Lluis, Tessier-Lavigne, Marc, Smith, Gregory A., Notarangelo, Luigi D., Studer, Lorenz, Gilbert, Wendy, Abel, Laurent, Casanova, Jean-Laurent, Zhang, Shen-Ying
Publicado no Nat Med (2019)

Inborn errors of RNA lariat metabolism in humans with brainstem viral infection

Por Zhang, Shen-Ying, Clark, Nathaniel E., Freije, Catherine A., Pauwels, Elodie, Taggart, Allison, Okada, Satoshi, Mandel, Hanna, Garcia, Paula, Ciancanelli, Michael J., Biran, Anat, Lafaille, Fabien G., Tsumura, Miyuki, Cobat, Aurélie, Luo, Jingchuan, Volpi, Stefano, Zimmer, Bastian, Sakata, Sonoko, Dinis, Alexandra, Ohara, Osamu, Garcia Reino, Eduardo J., Dobbs, Kerry, Hasek, Mary, Holloway, Stephen P., McCammon, Karen, Hussong, Stacy A., DeRosa, Nicholas, Van Skike, Candice E., Katolik, Adam, Lorenzo, Lazaro, Hyodo, Maki, Faria, Emilia, Halwani, Rabih, Fukuhara, Rie, Smith, Gregory A., Galvan, Veronica, Damha, Masad J., Al-Muhsen, Saleh, Itan, Yuval, Boeke, Jef D., Notarangelo, Luigi D., Studer, Lorenz, Kobayashi, Masao, Diogo, Luisa, Fairbrother, William, Abel, Laurent, Rosenberg, Brad, Hart, John, Etzioni, Amos, Casanova, Jean-Laurent
Publicado no Cell (2018)