Evaluation of Developmental Toxicants and Signaling Pathways in a Functional Test Based on the Migration of Human Neural Crest Cells

Background: Information on the potential developmental toxicity (DT) of the majority of chemicals is scarce, and test capacities for further animal-based testing are limited. Therefore, new approaches with higher throughput are required. A screening strategy based on the use of relevant human cell t...

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Detalhes bibliográficos
Main Authors: Zimmer, Bastian, Lee, Gabsang, Balmer, Nina V, Meganathan, Kesavan, Sachinidis, Agapios, Studer, Lorenz, Leist, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440079/
https://ncbi.nlm.nih.gov/pubmed/22571897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1104489
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