STARTing to understand MLN64 function in cholesterol transport

Por Rigotti, Attilio, Cohen, David E., Zanlungo, Silvana
Publicado em 2010

Molecular Mechanisms Underlying the Link between Nuclear Receptor Function and Cholesterol Gallstone Formation

Por Vázquez, Mary Carmen, Rigotti, Attilio, Zanlungo, Silvana
Publicado em 2012

Oxidative Stress: A Pathogenic Mechanism for Niemann-Pick Type C Disease

Por Vázquez, Mary Carmen, Balboa, Elisa, Alvarez, Alejandra R., Zanlungo, Silvana
Publicado em 2012

Metabolic Effects of Cholecystectomy: Gallbladder Ablation Increases Basal Metabolic Rate through G-Protein Coupled Bile Acid Receptor Gpbar1-Dependent Mechanisms in Mice

Por Cortés, Víctor, Amigo, Ludwig, Zanlungo, Silvana, Galgani, José, Robledo, Fermín, Arrese, Marco, Bozinovic, Francisco, Nervi, Flavio
Publicado no PLoS One (2015)

Fecal bile acid excretion and messenger RNA expression levels of ileal transporters in high risk gallstone patients

Por Herrera, Jorge, Amigo, Ludwig, Husche, Constanze, Benítez, Carlos, Zanlungo, Silvana, Lütjohann, Dieter, Miquel, Juan Francisco, Nervi, Flavio
Publicado em 2009

Alteration of Gene Expression Profile in Niemann-Pick Type C Mice Correlates with Tissue Damage and Oxidative Stress

Por Vázquez, Mary C., del Pozo, Talía, Robledo, Fermín A., Carrasco, Gonzalo, Pavez, Leonardo, Olivares, Felipe, González, Mauricio, Zanlungo, Silvana
Publicado em 2011

Vitamin E Dietary Supplementation Improves Neurological Symptoms and Decreases c-Abl/p73 Activation in Niemann-Pick C Mice

Por Marín, Tamara, Contreras, Pablo, Castro, Juan Francisco, Chamorro, David, Balboa, Elisa, Bosch-Morató, Mònica, Muñoz, Francisco J., Alvarez, Alejandra R., Zanlungo, Silvana
Publicado em 2014

Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway

Por Contreras, Pablo S., Gonzalez-Zuñiga, Marcelo, González-Hódar, Lila, Yáñez, María José, Dulcey, Andrés, Marugan, Juan, Seto, Edward, Alvarez, Alejandra R., Zanlungo, Silvana
Publicado no Biochim Biophys Acta (2015)

Cholinergic Abnormalities, Endosomal Alterations and Up-Regulation of Nerve Growth Factor Signaling in Niemann-Pick Type C Disease

Por Cabeza Carolina, Figueroa Alicia, Lazo Oscar M, Galleguillos Carolina, Pissani Claudia, Klein Andrés, Gonzalez-Billault Christian, Inestrosa Nibaldo C, Alvarez Alejandra R, Zanlungo Silvana, Bronfman Francisca C
Publicado em 2012-03-01

Cholinergic Abnormalities, Endosomal Alterations and Up-Regulation of Nerve Growth Factor Signaling in Niemann-Pick Type C Disease

Por Cabeza, Carolina, Figueroa, Alicia, Lazo, Oscar M, Galleguillos, Carolina, Pissani, Claudia, Klein, Andrés, Gonzalez-Billault, Christian, Inestrosa, Nibaldo C, Alvarez, Alejandra R, Zanlungo, Silvana, Bronfman, Francisca C
Publicado em 2012

Disruption in Connexin-Based Communication Is Associated with Intracellular Ca(2+) Signal Alterations in Astrocytes from Niemann-Pick Type C Mice

Por Sáez, Pablo J., Orellana, Juan A., Vega-Riveros, Natalia, Figueroa, Vania A., Hernández, Diego E., Castro, Juan F., Klein, Andrés D., Jiang, Jean X., Zanlungo, Silvana, Sáez, Juan C.
Publicado em 2013

Overexpression of the cholesterol-binding protein MLN64 induces liver damage in the mouse

Por Tichauer, Juan Enrique, Morales, María Gabriela, Amigo, Ludwig, Galdames, Leopoldo, Klein, Andrés, Quiñones, Verónica, Ferrada, Carla, R, Alejandra Alvarez, Rio, Marie-Christine, Miquel, Juan Francisco, Rigotti, Attilio, Zanlungo, Silvana
Publicado em 2007

MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content

Por Balboa, Elisa, Castro, Juan, Pinochet, María-José, Cancino, Gonzalo I., Matías, Nuria, José Sáez, Pablo, Martínez, Alexis, Álvarez, Alejandra R., Garcia-Ruiz, Carmen, Fernandez-Checa, José C., Zanlungo, Silvana
Publicado no Redox Biol (2017)

Epidemiological, clinical and biochemical characterization of the p.(Ala359Asp) SMPD1 variant causing Niemann–Pick disease type B

Por Acuña, Mariana, Martínez, Pablo, Moraga, Carol, He, Xingxuan, Moraga, Mauricio, Hunter, Bessie, Nuernberg, Peter, Gutiérrez, Rodrigo A, González, Mauricio, Schuchman, Edward H, Luis Santos, José, Miquel, Juan Francisco, Mabe, Paulina, Zanlungo, Silvana
Publicado no Eur J Hum Genet (2016)

Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease

Por Torres, Sandra, Matías, Nuria, Baulies, Anna, Nuñez, Susana, Alarcon-Vila, Cristina, Martinez, Laura, Nuño, Natalia, Fernandez, Anna, Caballeria, Joan, Levade, Thierry, Gonzalez-Franquesa, Alba, Garcia-Rovés, Pablo, Balboa, Elisa, Zanlungo, Silvana, Fabrías, Gemma, Casas, Josefina, Enrich, Carlos, Garcia-Ruiz, Carmen, Fernández-Checa, José C.
Publicado no Redox Biol (2016)