Metabolic Effects of Cholecystectomy: Gallbladder Ablation Increases Basal Metabolic Rate through G-Protein Coupled Bile Acid Receptor Gpbar1-Dependent Mechanisms in Mice

BACKGROUND & AIMS: Bile acids (BAs) regulate energy expenditure by activating G-protein Coupled Bile Acid Receptor Gpbar1/TGR5 by cAMP-dependent mechanisms. Cholecystectomy (XGB) increases BAs recirculation rates resulting in increased tissue exposure to BAs during the light phase of the diurnal...

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Vydáno v:PLoS One
Hlavní autoři: Cortés, Víctor, Amigo, Ludwig, Zanlungo, Silvana, Galgani, José, Robledo, Fermín, Arrese, Marco, Bozinovic, Francisco, Nervi, Flavio
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349594/
https://ncbi.nlm.nih.gov/pubmed/25738495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118478
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