Controversies on the potential therapeutic use of rapamycin for treating a lysosomal cholesterol storage disease

Por Calderón, Juan F., Klein, Andrés D.
Publicado no Mol Genet Metab Rep (2018)

Is Parkinson’s disease a lysosomal disorder?

Por Klein, Andrés D, Mazzulli, Joseph R
Publicado no Brain (2018)

Complement is dispensable for neurodegeneration in Niemann-Pick disease type C

Por Lopez, Manuel E, Klein, Andres D, Scott, Matthew P
Publicado em 2012

Anatomically Defined Neuron-Based Rescue of Neurodegenerative Niemann–Pick Type C Disorder

Por Lopez, Manuel E., Klein, Andres D., Dimbil, Ubah J., Scott, Matthew P.
Publicado em 2011

Neuronal and epithelial cell rescue resolves chronic systemic inflammation in the lipid storage disorder Niemann-Pick C

Por Lopez, Manuel E., Klein, Andrés D., Hong, Jennifer, Dimbil, Ubah J., Scott, Matthew P.
Publicado em 2012

Cholinergic Abnormalities, Endosomal Alterations and Up-Regulation of Nerve Growth Factor Signaling in Niemann-Pick Type C Disease

Por Cabeza Carolina, Figueroa Alicia, Lazo Oscar M, Galleguillos Carolina, Pissani Claudia, Klein Andrés, Gonzalez-Billault Christian, Inestrosa Nibaldo C, Alvarez Alejandra R, Zanlungo Silvana, Bronfman Francisca C
Publicado em 2012-03-01

Cholinergic Abnormalities, Endosomal Alterations and Up-Regulation of Nerve Growth Factor Signaling in Niemann-Pick Type C Disease

Por Cabeza, Carolina, Figueroa, Alicia, Lazo, Oscar M, Galleguillos, Carolina, Pissani, Claudia, Klein, Andrés, Gonzalez-Billault, Christian, Inestrosa, Nibaldo C, Alvarez, Alejandra R, Zanlungo, Silvana, Bronfman, Francisca C
Publicado em 2012

Disruption in Connexin-Based Communication Is Associated with Intracellular Ca(2+) Signal Alterations in Astrocytes from Niemann-Pick Type C Mice

Por Sáez, Pablo J., Orellana, Juan A., Vega-Riveros, Natalia, Figueroa, Vania A., Hernández, Diego E., Castro, Juan F., Klein, Andrés D., Jiang, Jean X., Zanlungo, Silvana, Sáez, Juan C.
Publicado em 2013

Overexpression of the cholesterol-binding protein MLN64 induces liver damage in the mouse

Por Tichauer, Juan Enrique, Morales, María Gabriela, Amigo, Ludwig, Galdames, Leopoldo, Klein, Andrés, Quiñones, Verónica, Ferrada, Carla, R, Alejandra Alvarez, Rio, Marie-Christine, Miquel, Juan Francisco, Rigotti, Attilio, Zanlungo, Silvana
Publicado em 2007

Reduced ceramide synthase 2 activity causes progressive myoclonic epilepsy

Por Mosbech, Mai-Britt, Olsen, Anne S B, Neess, Ditte, Ben-David, Oshrit, Klitten, Laura L, Larsen, Jan, Sabers, Anne, Vissing, John, Nielsen, Jørgen E, Hasholt, Lis, Klein, Andres D, Tsoory, Michael M, Hjalgrim, Helle, Tommerup, Niels, Futerman, Anthony H, Møller, Rikke S, Færgeman, Nils J
Publicado em 2014