Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease

Niemann Pick type C (NPC) disease is a progressive lysosomal storage disorder caused by mutations in genes encoding NPC1/NPC2 proteins, characterized by neurological defects, hepatosplenomegaly and premature death. While the primary biochemical feature of NPC disease is the intracellular accumulatio...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Redox Biol
Huvudupphovsmän: Torres, Sandra, Matías, Nuria, Baulies, Anna, Nuñez, Susana, Alarcon-Vila, Cristina, Martinez, Laura, Nuño, Natalia, Fernandez, Anna, Caballeria, Joan, Levade, Thierry, Gonzalez-Franquesa, Alba, Garcia-Rovés, Pablo, Balboa, Elisa, Zanlungo, Silvana, Fabrías, Gemma, Casas, Josefina, Enrich, Carlos, Garcia-Ruiz, Carmen, Fernández-Checa, José C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123076/
https://ncbi.nlm.nih.gov/pubmed/27888692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.11.010
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk