Beyond the Aryl Hydrocarbon Receptor: Pathway Interactions in the Hepatotoxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Related Compounds

Por Fader, Kelly A., Zacharewski, Timothy R.
Publicado no Curr Opin Toxicol (2017)

Comparison of TCDD-elicited genome-wide hepatic gene expression in Sprague–Dawley rats and C57BL/6 mice

Por Nault, Rance, Kim, Suntae, Zacharewski, Timothy R.
Publicado em 2012

TCDD-Elicited Effects on Liver, Serum, and Adipose Lipid Composition in C57BL/6 Mice

Por Angrish, Michelle Manente, Dominici, Claudia Yvette, Zacharewski, Timothy Richard
Publicado em 2013

Comparisons of differential gene expression elicited by TCDD, PCB126, βNF, or ICZ in mouse hepatoma Hepa1c1c7 cells and C57BL/6 mouse liver

Por Nault, Rance, Forgacs, Agnes L., Dere, Edward, Zacharewski, Timothy R.
Publicado em 2013

In vivo – in vitro toxicogenomic comparison of TCDD-elicited gene expression in Hepa1c1c7 mouse hepatoma cells and C57BL/6 hepatic tissue

Por Dere, Edward, Boverhof, Darrell R, Burgoon, Lyle D, Zacharewski, Timothy R
Publicado em 2006

Differences in TCDD-elicited gene expression profiles in human HepG2, mouse Hepa1c1c7 and rat H4IIE hepatoma cells

Por Dere, Edward, Lee, Andrea W, Burgoon, Lyle D, Zacharewski, Timothy R
Publicado em 2011

Integration of Genome-Wide Computation DRE Search, AhR ChIP-chip and Gene Expression Analyses of TCDD-Elicited Responses in the Mouse Liver

Por Dere, Edward, Lo, Raymond, Celius, Trine, Matthews, Jason, Zacharewski, Timothy R
Publicado em 2011

Comparative Analysis of Temporal and Dose-Dependent TCDD-Elicited Gene Expression in Human, Mouse, and Rat Primary Hepatocytes

Por Forgacs, Agnes L., Dere, Edward, Angrish, Michelle M., Zacharewski, Timothy R.
Publicado em 2013

Genome-Wide Computational Analysis of Dioxin Response Element Location and Distribution in the Human, Mouse and Rat Genomes

Por Dere, Edward, Forgacs, Agnes L, Zacharewski, Timothy R, Burgoon, Lyle D
Publicado em 2011

Assessment of clone identity and sequence fidelity for 1189 IMAGE cDNA clones

Por Halgren, Robert G., Fielden, Mark R., Fong, Cora J., Zacharewski, Timothy R.
Publicado em 2001

Aryl Hydrocarbon Receptor–Mediated Induction of Stearoyl-CoA Desaturase 1 Alters Hepatic Fatty Acid Composition in TCDD-Elicited Steatosis

Por Angrish, Michelle M., Jones, A.D., Harkema, Jack R., Zacharewski, Timothy R.
Publicado em 2011

Dietary Fat Is a Lipid Source in 2,3,7,8-Tetrachlorodibenzo-ρ-Dioxin (TCDD)-Elicited Hepatic Steatosis in C57BL/6 Mice

Por Angrish, Michelle Manente, Mets, Bryan David, Jones, Arthur Daniel, Zacharewski, Timothy Richard
Publicado em 2012

Development of a Computational High-Throughput Tool for the Quantitative Examination of Dose-Dependent Histological Features

Por Nault, Rance, Colbry, Dirk, Brandenberger, Christina, Harkema, Jack R., Zacharewski, Timothy R.
Publicado no Toxicol Pathol (2014)

Comparative Analysis of TCDD-Induced AhR-Mediated Gene Expression in Human, Mouse and Rat Primary B Cells

Por Kovalova, Natalia, Nault, Rance, Crawford, Robert, Zacharewski, Timothy R., Kaminski, Norbert E.
Publicado no Toxicol Appl Pharmacol (2016)

Comparative Analysis of AhR-Mediated TCDD-Elicited Gene Expression in Human Liver Adult Stem Cells

Por Kim, Suntae, Dere, Edward, Burgoon, Lyle D., Chang, Chia-Cheng, Zacharewski, Timothy R.
Publicado em 2009

Comparative temporal and dose-dependent morphological and transcriptional uterine effects elicited by tamoxifen and ethynylestradiol in immature, ovariectomized mice

Por Fong, Cora J, Burgoon, Lyle D, Williams, Kurt J, Forgacs, Agnes L, Zacharewski, Timothy R
Publicado em 2007

Tamoxifen-elicited uterotrophy: cross-species and cross-ligand analysis of the gene expression program

Por Kwekel, Joshua C, Forgacs, Agnes L, Burgoon, Lyle D, Williams, Kurt J, Zacharewski, Timothy R
Publicado em 2009

Effects of TCDD on the Expression of Nuclear Encoded Mitochondrial Genes

Por Forgacs, Agnes L., Burgoon, Lyle D., Lynn, Scott G., LaPres, John J., Zacharewski, Timothy
Publicado em 2010

Convergence of Hepcidin Deficiency, Systemic Iron Overloading, Heme Accumulation, and REV-ERBα/β Activation in Aryl Hydrocarbon Receptor-Elicited Hepatotoxicity

Por Fader, Kelly A., Nault, Rance, Kirby, Mathew P., Markous, Gena, Matthews, Jason, Zacharewski, Timothy R.
Publicado no Toxicol Appl Pharmacol (2017)

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-elicited effects on bile acid homeostasis: Alterations in biosynthesis, enterohepatic circulation, and microbial metabolism

Por Fader, Kelly A., Nault, Rance, Zhang, Chen, Kumagai, Kazuyoshi, Harkema, Jack R., Zacharewski, Timothy R.
Publicado no Sci Rep (2017)