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Beyond the Aryl Hydrocarbon Receptor: Pathway Interactions in the Hepatotoxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Related Compounds

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is the prototypical ligand for a group of environmental halogenated aromatic hydrocarbon contaminants which elicit hepatotoxicity and other toxic responses through activation of the aryl hydrocarbon receptor (AhR). Despite the conservation of the AhR and it...

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Detalhes bibliográficos
Publicado no:Curr Opin Toxicol
Main Authors: Fader, Kelly A., Zacharewski, Timothy R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609723/
https://ncbi.nlm.nih.gov/pubmed/28948239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cotox.2017.01.010
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