2,3,7,8-Tetrachlorodibenzo-p-dioxin enhances CCl(4)-induced hepatotoxicity in an aryl hydrocarbon receptor-dependent manner

Cytochrome P4502E1 (CYP2E1) is involved in the biotransformation of several low molecular weight chemicals and plays an important role in the metabolic activation of carcinogens and hepatotoxins such as CCl(4). Induction of CYP2E1 is exerted mainly at posttranscriptional levels through mRNA and prot...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Xenobiotica
Main Authors: Mejia-Garcia, Alejandro, Sanchez-Ocampo, Esmeralda M., Galindo-Gomez, Silvia, Shibayama, Mineko, Reyes-Hernandez, Octavio, Guzman-Leon, Simon, Gonzalez, Frank J., Elizondo, Guillermo
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319626/
https://ncbi.nlm.nih.gov/pubmed/22834477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2012.707790
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