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2,3,7,8-Tetrachlorodibenzo-p-dioxin enhances CCl(4)-induced hepatotoxicity in an aryl hydrocarbon receptor-dependent manner
Cytochrome P4502E1 (CYP2E1) is involved in the biotransformation of several low molecular weight chemicals and plays an important role in the metabolic activation of carcinogens and hepatotoxins such as CCl(4). Induction of CYP2E1 is exerted mainly at posttranscriptional levels through mRNA and prot...
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| Publicat a: | Xenobiotica |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6319626/ https://ncbi.nlm.nih.gov/pubmed/22834477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2012.707790 |
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