Differences in TCDD-elicited gene expression profiles in human HepG2, mouse Hepa1c1c7 and rat H4IIE hepatoma cells

BACKGROUND: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is an environmental contaminant that elicits a broad spectrum of toxic effects in a species-specific manner. Current risk assessment practices routinely extrapolate results from in vivo and in vitro rodent models to assess human risk. In order t...

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Hlavní autoři: Dere, Edward, Lee, Andrea W, Burgoon, Lyle D, Zacharewski, Timothy R
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089798/
https://ncbi.nlm.nih.gov/pubmed/21496263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-193
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