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Polarization Restricts Hepatitis C Virus Entry into HepG2 Hepatoma Cells

The primary reservoir for hepatitis C virus (HCV) replication is believed to be hepatocytes, which are highly polarized with tight junctions (TJ) separating their basolateral and apical domains. HepG2 cells develop polarity over time, resulting in the formation and remodeling of bile canalicular (BC...

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Bibliografski detalji
Glavni autori: Mee, Christopher J., Harris, Helen J., Farquhar, Michelle J., Wilson, Garrick, Reynolds, Gary, Davis, Christopher, van IJzendoorn, Sven C. D., Balfe, Peter, McKeating, Jane A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687400/
https://ncbi.nlm.nih.gov/pubmed/19357163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00246-09
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