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Polarization Restricts Hepatitis C Virus Entry into HepG2 Hepatoma Cells

The primary reservoir for hepatitis C virus (HCV) replication is believed to be hepatocytes, which are highly polarized with tight junctions (TJ) separating their basolateral and apical domains. HepG2 cells develop polarity over time, resulting in the formation and remodeling of bile canalicular (BC...

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Detalhes bibliográficos
Main Authors: Mee, Christopher J., Harris, Helen J., Farquhar, Michelle J., Wilson, Garrick, Reynolds, Gary, Davis, Christopher, van IJzendoorn, Sven C. D., Balfe, Peter, McKeating, Jane A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687400/
https://ncbi.nlm.nih.gov/pubmed/19357163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00246-09
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