Protein Kinase A-Dependent Step(s) in Hepatitis C Virus Entry and Infectivity

Viruses exploit signaling pathways to their advantage during multiple stages of their life cycle. We demonstrate a role for protein kinase A (PKA) in the hepatitis C virus (HCV) life cycle. The inhibition of PKA with H89, cyclic AMP (cAMP) antagonists, or the protein kinase inhibitor peptide reduced...

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Detalhes bibliográficos
Main Authors: Farquhar, Michelle J., Harris, Helen J., Diskar, Mandy, Jones, Sarah, Mee, Christopher J., Nielsen, Søren U., Brimacombe, Claire L., Molina, Sonia, Toms, Geoffrey L., Maurel, Patrick, Howl, John, Herberg, Friedrich W., van IJzendoorn, Sven C. D., Balfe, Peter, McKeating, Jane A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519651/
https://ncbi.nlm.nih.gov/pubmed/18579596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00592-08
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