Protein Kinase A-Dependent Step(s) in Hepatitis C Virus Entry and Infectivity

Viruses exploit signaling pathways to their advantage during multiple stages of their life cycle. We demonstrate a role for protein kinase A (PKA) in the hepatitis C virus (HCV) life cycle. The inhibition of PKA with H89, cyclic AMP (cAMP) antagonists, or the protein kinase inhibitor peptide reduced...

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Main Authors: Farquhar, Michelle J., Harris, Helen J., Diskar, Mandy, Jones, Sarah, Mee, Christopher J., Nielsen, Søren U., Brimacombe, Claire L., Molina, Sonia, Toms, Geoffrey L., Maurel, Patrick, Howl, John, Herberg, Friedrich W., van IJzendoorn, Sven C. D., Balfe, Peter, McKeating, Jane A.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2008
主題:
Virus-Cell Interactions
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519651/
https://ncbi.nlm.nih.gov/pubmed/18579596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00592-08
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