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Protein Kinase A-Dependent Step(s) in Hepatitis C Virus Entry and Infectivity

Viruses exploit signaling pathways to their advantage during multiple stages of their life cycle. We demonstrate a role for protein kinase A (PKA) in the hepatitis C virus (HCV) life cycle. The inhibition of PKA with H89, cyclic AMP (cAMP) antagonists, or the protein kinase inhibitor peptide reduced...

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Autori principali: Farquhar, Michelle J., Harris, Helen J., Diskar, Mandy, Jones, Sarah, Mee, Christopher J., Nielsen, Søren U., Brimacombe, Claire L., Molina, Sonia, Toms, Geoffrey L., Maurel, Patrick, Howl, John, Herberg, Friedrich W., van IJzendoorn, Sven C. D., Balfe, Peter, McKeating, Jane A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519651/
https://ncbi.nlm.nih.gov/pubmed/18579596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00592-08
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