Crosstalk between Insulin Receptor and G protein-Coupled Receptor Signaling Systems Leads to Ca(2+) Oscillations in Pancreatic Cancer PANC-1 Cells

Por Young, Steven H., Rozengurt, Enrique
Publicado em 2010

Intracellular Ca(2+) oscillations generated via the extracellular Ca(2+)-sensing receptor (CaSR) in response to extracellular Ca(2+) or L-phenylalanine: impact of the highly conser...

Por Young, Steven H., Rey, Osvaldo, Rozengurt, Enrique
Publicado no Biochem Biophys Res Commun (2015)

Amino acid sensing by enteroendocrine STC-1 cells: role of the Na(+)-coupled neutral amino acid transporter 2

Por Young, Steven H., Rey, Osvaldo, Sternini, Catia, Rozengurt, Enrique
Publicado em 2010

Rapid protein kinase D1 signaling promotes migration of intestinal epithelial cells

Por Young, Steven H., Rozengurt, Nora, Sinnett-Smith, James, Rozengurt, Enrique
Publicado em 2012

PKD1 Mediates Negative Feedback of PI3K/Akt Activation in Response to G Protein-Coupled Receptors

Por Ni, Yang, Sinnett-Smith, James, Young, Steven H., Rozengurt, Enrique
Publicado em 2013

Correction: PKD1 Mediates Negative Feedback of PI3K/Akt Activation in Response to G Protein-Coupled Receptors

Por Ni, Yang, Sinnett-Smith, James, Young, Steven H., Rozengurt, Enrique
Publicado em 2014

Intracellular Ca(2+) oscillations generated via the Ca(2+)-sensing receptor are mediated by negative feedback by PKCα at Thr(888)

Por Young, Steven H., Rey, Osvaldo, Sinnett-Smith, James, Rozengurt, Enrique
Publicado em 2013

EXTRACELLULAR CALCIUM SENSING RECEPTOR STIMULATION IN HUMAN COLONIC EPITHELIAL CELLS INDUCES INTRACELLULAR CALCIUM OSCILLATIONS AND PROLIFERATION INHIBITION

Por Rey, Osvaldo, Young, Steven H., Jacamo, Rodrigo, Moyer, Mary P, Rozengurt, Enrique
Publicado em 2010

Negative Cross-talk between Calcium-sensing Receptor and β-Catenin Signaling Systems in Colonic Epithelium

Por Rey, Osvaldo, Chang, Wenhan, Bikle, Daniel, Rozengurt, Nora, Young, Steven H., Rozengurt, Enrique
Publicado em 2012

Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NO...

Por Wang, Jia, Sinnett-Smith, James, Stevens, Jan V., Young, Steven H., Rozengurt, Enrique
Publicado no J Biol Chem (2016)

Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells

Por Wu, S. Vincent, Rozengurt, Nora, Yang, Moon, Young, Steven H., Sinnett-Smith, James, Rozengurt, Enrique
Publicado em 2002

HLA class I-mediated stress fiber formation requires ERK1/2 activation in the absence of an increase in intracellular Ca(2+) in human aortic endothelial cells

Por Ziegler, Mary E., Jin, Yi-Ping, Young, Steven H., Rozengurt, Enrique, Reed, Elaine F.
Publicado em 2012

Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signaling

Por Sinnett-Smith, James, Ni, Yang, Wang, Jia, Ming, Ming, Young, Steven H., Rozengurt, Enrique
Publicado em 2014

Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells

Por Ming, Ming, Sinnett-Smith, James, Wang, Jia, Soares, Heloisa P., Young, Steven H., Eibl, Guido, Rozengurt, Enrique
Publicado no PLoS One (2014)

Dual PI3K/mTOR inhibitors induce rapid over-activation of the MEK/ERK pathway in human pancreatic cancer cells through suppression of mTORC2

Por Soares, Heloisa P., Ming, Ming, Mellon, Michelle, Young, Steven H., Han, Liang, Sinnet-Smith, James, Rozengurt, Enrique
Publicado no Mol Cancer Ther (2015)

Insulin Receptor and GPCR Crosstalk Stimulates YAP via PI3K and PKD in Pancreatic Cancer Cells

Por Hao, Fang, Xu, Qinhong, Zhao, Yinglan, Stevens, Jan V., Young, Steven H., Sinnett-Smith, James, Rozengurt, Enrique
Publicado no Mol Cancer Res (2017)

Protein kinase D1 (PKD1) phosphorylation on Ser(203) by type I p21-activated kinase (PAK) regulates PKD1 localization

Por Chang, Jen-Kuan, Ni, Yang, Han, Liang, Sinnett-Smith, James, Jacamo, Rodrigo, Rey, Osvaldo, Young, Steven H., Rozengurt, Enrique
Publicado no J Biol Chem (2017)

Protein Kinase D Mediates Mitogenic Signaling by G(q)-coupled Receptors through Protein Kinase C-independent Regulation of Activation Loop Ser(744) and Ser(748) Phosphorylation

Por Sinnett-Smith, James, Jacamo, Rodrigo, Kui, Robert, Wang, YunZu M., Young, Steven H., Rey, Osvaldo, Waldron, Richard T., Rozengurt, Enrique
Publicado em 2009

Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser(552)

Por Wang, Jia, Han, Liang, Sinnett-Smith, James, Han, Li-Li, Stevens, Jan V., Rozengurt, Nora, Young, Steven H., Rozengurt, Enrique
Publicado no Am J Physiol Cell Physiol (2016)

Evidence for orphan nuclear receptor TR4 in the etiology of Cushing disease

Por Du, Li, Bergsneider, Marvin, Mirsadraei, Leili, Young, Steven H., Jonker, Johan W., Downes, Michael, Yong, William H., Evans, Ronald M., Heaney, Anthony P.
Publicado em 2013