Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells

Lignende værker

• Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK
  af: Sinnett-Smith, James, et al.
  Udgivet: (2012)
• Metformin, Independent of AMPK, Inhibits mTORC1 In a Rag GTPase-Dependent Manner
  af: Kalender, Adem, et al.
  Udgivet: (2010)
• MHC Class I and Integrin Ligation Induce ERK Activation Via an mTORC2-Dependent Pathway
  af: Jindra, Peter T., et al.
  Udgivet: (2008)
• Different Patterns of Akt and ERK Feedback Activation in Response to Rapamycin, Active-Site mTOR Inhibitors and Metformin in Pancreatic Cancer Cells
  af: Soares, Heloisa P., et al.
  Udgivet: (2013)
• Dual PI3K/mTOR inhibitors induce rapid over-activation of the MEK/ERK pathway in human pancreatic cancer cells through suppression of mTORC2
  af: Soares, Heloisa P., et al.
  Udgivet: (2015)